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2023 1

2022 1

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Bacillus subtilis 1

Genetic circuits 1

Isoprene pyrophosphate 1

Terpenoids 1

directed evolution 1

dynamic control 1

heat-shock 1

isoprene 1

transcriptional activator 1

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Development of a dual temperature control system for isoprene biosynthesis in

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 7,   Pages 1079-1089 doi: 10.1007/s11705-021-2088-0

Abstract: To address the growth-production conflict in yeast strains harboring the isoprene synthetic pathway inthe mitochondria, the dynamic control of isoprene biosynthesis was explored.Gal4p, the dual temperature regulation strategy led to 34.5% and 72% improvements in cell growth and isoprene

Keywords： transcriptional activator     directed evolution     dynamic control     heat-shock     isoprene    

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Remodeling Isoprene Pyrophosphate Metabolism for Promoting Terpenoids Bioproduction Article

Xianhao Xu, Xueqin Lv, Shixiu Cui, Yanfeng Liu, Hongzhi Xia, Jianghua Li, Guocheng Du, Zhaofeng Li, Rodrigo Ledesma-Amaro, Jian Chen, Long Liu

Engineering 2023, Volume 28, Issue 9,   Pages 166-178 doi: 10.1016/j.eng.2023.03.019

Abstract: They are made from the building block isoprene pyrophosphate (IPP), and their bioproduction using engineered

Keywords： Terpenoids     Genetic circuits     Bacillus subtilis     Isoprene pyrophosphate    

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Title Author Date Type Operation

Development of a dual temperature control system for isoprene biosynthesis in

Journal Article

Remodeling Isoprene Pyrophosphate Metabolism for Promoting Terpenoids Bioproduction

Xianhao Xu, Xueqin Lv, Shixiu Cui, Yanfeng Liu, Hongzhi Xia, Jianghua Li, Guocheng Du, Zhaofeng Li, Rodrigo Ledesma-Amaro, Jian Chen, Long Liu

Journal Article